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Bone loss during the fat loss period (fat loss model in obese rats) Experimental Design: Animals: Obese SD rats induced by high-fat diet were randomly divided into an obesity control group, a simple weight loss group (30% calorie restriction), and a weight loss+AOD 9604 group (500 g/kg/day)
Ideal for areas where hair looks weak, thin, or stressed
By selectively inhibiting NNMT activity, researchers study how changes in nicotinamide metabolism influence intracellular NAD availability, methylation balance, mitochondrial efficiency, and lipid metabolism
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