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EGR-1 is a gene that is considered to respond immediately and is potentially involved in the generation of cytokines and growth factors, as well as the early formation of extracellular matrix components like collagen

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Resorbable PCL splints have been successfully implanted with a comparable mortality rate and no reoperations in a more severe clinical population, compared to PTFE external splints.[101] Tracheal agenesis is another airway pathology where a supportive airway substitute is required with few viable solutions

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