An overdose might cause nausea, vomiting or upset stomach
This is usually not a problem
In contrast, individuals who develop malabsorption of vitamin E in adulthood may not develop neurological symptoms for 10 to 20 years
These injections also include nutrients like methionine, inositol, and choline, which help the body break down fats and use them for energy
Beyond GI effects, patients should watch for: Headaches , particularly during the first two weeks and after dose escalations Insomnia or sleep disruption, which affects some patients more than others Muscle pain and body aches , often reported in the first week of a new dose Anxiety , which some patients experience as appetite suppression creates unfamiliar hunger signals Joint pain , reported less frequently but worth monitoring Injection site reactions , including redness, itching, and localized swelling Menstrual changes , as rapid weight loss and hormonal shifts can affect cycle regularity Fatigue , especially during the caloric restriction phase Hair loss , a known but usually temporary effect of significant weight loss If side effects become unmanageable at any dose, the microdose tirzepatide schedule offers an alternative approach