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If needed, unopened pens may be stored at room temperature (59F to 86F or 15C to 30C) for up to 28 days in the original carton

Clinical trials and recent meta-analyses consistently show tirzepatide delivers the most substantial weight reduction among GLP-1 medications, with average losses of up to 22.5% of body weight

In fact, several medical societies have issued statements advising against using compounded GLP-1 drugs outside of very specific shortage-related circumstances

On average, patients experience a reduction in appetite once the medication is started, says Kushner

Most patients lose 10-20 lbs within the first 30 days when combined with healthy lifestyle habits