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Glutathione is the bodys master antioxidant a tripeptide synthesized in every cell that neutralizes reactive oxygen species, drives Phase II hepatic detoxification, supports immune function, and protects mitochondrial integrity

As IKK- is the direct upstream kinase that phosphorylates IB-, leading to its degradation, we next examined whether decreased TNF-induced IB- phosphorylation by H 2 O 2 treatment was due to its effects on IKK- activity

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Ballinger SW, Bouder TG, Davis GS, Judice SA, Nicklas JA, Albertini RJ