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The most important and most frequently used indication for DPP-4 inhibitors is their add-on use in patients who are not sufficiently controlled on metformin monotherapy (12, 1719, 21, 22)

In this case, the pill is taken daily

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Patients may experience increased salivation (sialorrhea) as a prodrome to nausea or vomiting, or conversely, may notice reduced appetite affecting their oral intake patterns