Clinicians should consider prioritising review for people with type 2 diabetes on the affected GLP-1 RA preparation where: HbA1c greater than 86mmol/mol in the previous 3 to 6 months HbA1c greater than 86mmol/mol prior to starting the GLP1-RA HbA1c not recorded in the previous 6 months Urine albumin creatinine ratio (uACR) greater than 30mg/mmol Self-monitoring glucose readings (or Continuous Glucose Monitoring, where available) are persistently above individualised target range
Consult a health care practitioner prior to use if you have been instructed to follow a low protein diet, or if you have a pre-existing seizure disorder, liver or kidney disease
Common side effects may include nausea, vomiting, diarrhea, constipation, and decreased appetite
Metformin slows glucose absorption in the intestines Metformin also helps by inhibiting sodium-glucose cotransporter 1 (SGLT1) , and this process helps reduce glucose absorption in the small intestine
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