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doi: 10.1111/j.1365-3164.2007.00647.x

Surg Today 38:716725 Park J, Hwang S, Yoon I (2017) Advanced growth factor delivery systems in wound management and skin regeneration

Long half-life (characterized in studies): Reported as long-acting in preclinical and clinical research, supporting extended-interval dosing within those study protocols

Prevotella are important producers of succinic acid, which has anti-inflammatory effects by suppressing IL-6, TNF-, IL-1, and nitric oxide production in macrophages, further supporting a microbemetaboliteimmune link in ASD [325, 326]

However, specific injuries such as traumatic brain injury, stroke, brain tumor, or aging are believed to compromise the efficiency of BBB protection, thereby allowing MSCs access to cross the BBB and deliver their protective effects