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The target is well-validated mechanistically

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S., Huo, J., & Zhang, W

There is a relationship of acidity and nucleophilic character of thiols with their disulfide-thiol oxidoreductive potential, by which those where the thiol group is more acidic, such as N- acetyl-cysteine are also those in which a more nucleophilic character of the thiolate sulphur also makes them more reactive in thiolate-disulfide exchange and therefore more effective as reducing agents [115,116]