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Summary The blood-brain barrier is an important structure that separates the brain and spinal cord (the central nervous system, or CNS) from the bloodstream The blood-brain barrier allows only selected molecules to pass, which makes therapy delivery to the brain more difficult Overcoming the blood-brain barrier may involve direct injection into the CNS, adapting a therapy to cross the blood-brain barrier from the blood, or using a delivery vehicle to carry a therapy across More information about therapy options for Sanfilippo can be found on our website

doi: 10.1089/thy.2020.0299 90 FaamBGhadiriAAGhaffariMATotonchiMKhorsandiL

Employers are beginning to recognize that covering these treatments can improve employee wellness and reduce long-term healthcare costs

Follow-up appointments allow healthcare providers to adjust the dosage if needed

Stopping treatment may lead to a return of previous appetite patterns