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in 2025, Scientific American reported an average weight loss of 15% for participants on Semaglutide, far exceeding that achieved with most behavioral interventions alone

Gastrointestinal Effects on Blood Clots Research shows that some gastrointestinal issues can increase a persons risk of developing blood clots

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During a 72-week study, conducted by the National Library of Medicine (NIH), Zepbound users lost 20.2% of their body weight on average, while Semaglutide users averaged 13.7% weight loss

However, Semaglutide is available in both oral and injectable forms, whereas Tirzepatide is only injectable