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Vet J Ruaux, C (2013) Cobalamin in companion animals: Diagnostic marker, deficiency states and therapeutic implications

The metabolism and clearance of both components may be affected by significant liver disease, and patients with severe hepatic impairment should be monitored closely if treatment is deemed necessary

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Reasoning: The reclassification was approved to allow pharmacists to supply the product without a prescription for the initial treatment of stable, mild-to-moderate plaque psoriasis in adults, increasing self-care options

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