Virus The AAV virus used in this study was pAAV-hSyn-EGFP-2A-Cre-WPRE, purchased from Vigene Biosciences (Shanghai) Co., Ltd
Drug Interactions The concomitant use of JANUMET XR with specific drugs may increase the risk of metformin-associated lactic acidosis: those that impair renal function, result in significant hemodynamic change, interfere with acid-base balance or increase metformin accumulation [see Drug Interactions (7)]
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Source for the acetate, propionate, and butyrate cross-feeding correction) Tolhurst G, Heffron H, Lam YS, et al
The combination of daily home monitoring and quarterly laboratory testing provides comprehensive assessment without excessive testing burden