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(ii) down-regulation of K + buffering resulting a neuronal hyper-excitability that disturbs circuit function and increases excitotoxic potential 128

Aging, poor diet, chronic illness, stress, sleep deprivation, and exposure to toxins can all contribute to low glutathione over time

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Regulatory history: Sermorelin was FDA-approved in 1997 under the brand name Geref for the treatment of growth hormone deficiency in children

The graduated dose titration schedule (starting at 0.6 mg daily and increasing weekly to the maintenance dose of 3.0 mg) is specifically designed to minimise gastrointestinal intolerance