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According to Johnson, incumbents are looking beyond the first generation of GLP-1 therapies, pursuing oral formulations and new delivery mechanisms to maintain their market leadership

But one active clinical trial, registered as NCT07092605 on ClinicalTrials.gov, is now specifically studying the effectiveness of microdosed GLP-1 receptor agonists for improving health and quality of life in patients who do not meet traditional prescribing criteria

Valuations for the two pharmaceutical companies (Novo Nordisk and Eli Lilly) at the core of this trend have rapidly increased as a result