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The New York Times reported that in one clinical trial, 63 percent of patients taking Wegovy showed clearance of fat and inflammation in the liver without worsening of scarring, compared to 34 percent in the placebo group

Even as the clinical community works to establish the long-term benefits of current GLP-1 and HRT combinations, a new generation of metabolic therapies is already moving through trials, ones that extend the biological logic of this article's central argument into territory that semaglutide and tirzepatide alone cannot reach

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