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Side-effect profiles The tolerability of these medicines also influences their long-term use

One of the more impressive highlights from these studies was that approximately one-third of subjects on the highest dosage of Zepbound experienced weight loss exceeding more than 25% of their body weight

Secondary endpoints included the proportion of participants achieving at least 10, 15, 20, and 25 percent weight loss, change in waist circumference, and improvement in cardiometabolic risk factors such as blood pressure and lipid profiles

Dosages are patient-specific but generally fall within a well-established therapeutic window

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