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The association of irAEs and clinical outcomes in NSCLC patients with existing brain metastasis who received ICIs is also not well studied

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The thing is that these injections are applied to stimulate metabolic processes in cells and prevent oxidative stress

10.1002/ange.201903981 62 WangD.WuH.WangC.GuL.ChenH.JanaD.et al (2021)

Abbreviations AMPK: AMP-activated protein kinase COX II: Cytochrome c oxidase subunit II mtDNA: Mitochondrial DNA NEFA: Nonesterified fatty acid PCR: Polymerase chain reaction PGC-1: Peroxisome proliferator-activated receptor- coactivator-1 RPE: Rating of perceived exertion VAS: visual analogue scale References Meister A