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Its active ingredient is tirzepatide, which is both a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist and a GLP-1 receptor agonist

Studies examining receptor dynamics have shown that the degree of desensitization varies among tissue types and may be influenced by dose and duration of exposure

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Microscopic observations confirmed the synergistic efficacy, revealing a higher percentage of cells undergoing apoptosis in the combination groups

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