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In the absence of safety data, most clinicians advise that pregnant or breastfeeding individuals avoid this compounded preparation unless the anticipated benefit clearly outweighs theoretical fetal or neonatal risks
Storing it below 2C risks freezing (more on that disastrous scenario later), while temperatures above 8C can begin to reduce the efficacy of the benzyl alcohol over time
One 10 mg vial provides roughly 1620 days of material at the 600 mcg/day target, and longer during the ramp weeks
Specically, path A is inactive because the energy barrier associated with direct dissociation of the methyl ligand is higher than the barrier of intersection between two dierent electronic states: a metal-to-ligand charge transfer state (MLCT), and a ligand eld state (LF) along the CoO coordinate of the S 1 PES
