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Multi-organ dysfunction syndrome (MODS) MODS due to virus-induced extensive tissue injury has long-term implications in COVID-19 survivors and in PASC

While it is known that skin cells can produce estrogens locally, aromatase enzyme activity is dramatically reduced to approximately 30 times lower than in premenopausal ovarian follicular tissue [10]

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In reserpinized animals, the number of squares crossed, grooming, raising, sniffing, and mobile time were considerably reduced, while the central immobility time was significantly enhanced compared to the control group