However, baseline homocysteine levels tend to be lower in people with Down syndrome than people without Down syndrome
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doi: 10.1183/13993003.03755-2020 46 RobertsHWhitePDiasIMcKaigSVeeramachaneniRThakkerNet al
TNF and sTNFR1/2 plasma levels in ALS patients
1991 (landmark Italian trial): A double-blind, placebo-controlled trial involving 130 patients with Alzheimer's disease demonstrated that one year of ALCAR treatment resulted in a slower rate of deterioration compared to placebo across 13 of 14 outcome measures, including significant improvements in the Blessed Dementia Scale, logical intelligence, verbal critical abilities, long-term verbal memory, and selective attention [5][17]