Obesity and metabolic disease carry particular health burdens for men, including increased risk of type 2 diabetes, cardiovascular disease, obstructive sleep apnoea, and hypogonadism (low testosterone)
One randomized placebo-controlled trial that assessed the effect of oral lipoic acid supplementation in 58 patients diagnosed with metabolic syndrome, a condition characterized by abnormal glucose and lipid metabolism, showed that flow-mediated vasodilation improved by 44% with 300 mg/day of lipoic acid for four weeks (66)
[10] For many patients, that slower pace is a fair trade-off for avoiding the severe nausea that often accompanies higher doses
Participants with better blood sugar control were also more likely to lose weight, highlighting the potential for dual action in type 2 diabetes care
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