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In addition to physical benefits, NAD+ plays a key role in mood regulation by boosting s erotonin productionhelping to ease symptoms of anxiety, depression, and stress-related fatigue

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This would provide much-needed human safety and efficacy data

Kennedy Crispin M, Ko J, Craiglow B, Li S, Shankar G, Urban J, Chen J, Cerise J, Jabbari A, Winge M, Marinkovich M, Christiano A, Oro A, King B (2016) Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata