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Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
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This imbalance affects metabolism, temperature regulation, and immune function, influencing many systems in the body
The synergistic effects were achieved by regulating AD-related pathways and genes more broadly and profoundly
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NAPDH Oxidase converts oxygen to Super Oxide (O 2 ) mainly in neutrophils Myeloperoxidase (MPO) converts peroxide (H2O2) into Hydrochloric Acid (HOCl) mainly in neutrophils Fenton Reaction generates Hydroxide (OH-) from peroxide (H2O2) using iron Superoxide Dismutase (SOD) converts Super Oxide (O 2 ) to peroxide (H2O2) Glutathione convert Hydroxide (OH-) to water Catalase converts Peroxide (H2O2) to water We will see in the immunology section that that a defect in NADPH Oxidase causes Chronic Granulomatous disease
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