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PD, perhaps more than any other NDD, exemplifies the concept that neurological diseases are not restricted to the brain but are truly systemic disorders involving the gut-brain axis

No participant had significant gastrointestinal symptoms, impaired renal or liver function, a history of gastrointestinal surgery, or a requirement for medication that is known to affect gastrointestinal function or appetite

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Other symptoms of deficiency may include inflammation, headaches, skeletal disorders, and nearsightedness

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