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Sun Y, Liu H, Gao Y, Sang H, Kong Q

4,13,62 Severe SS usually only occurs with the concomitant administration of 2 or more serotonergic drugs (even at therapeutic doses) (Table 2), with the combination of serotonergic drugs with MAOIs being especially dangerous, causing serious adverse outcome including death

Accordingly, Article 4.2.3 was added to the 2021 Code defining Substances of Abuse as those Prohibited Substances which are specifically identified as Substances of Abuse on the Prohibited List because they are frequently abused in society outside of the context of sport.

& Regnier, C