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No injectable or systemic human safety data

The mechanisms leading to OTA nephrotoxicity as well as its hepatotoxicity and immunotoxicity can be linked to the inhibition of protein synthesis, lipid peroxidation, and the modulation of the MAP kinase cascade, in a way similar to the exposure to pentachlorophenol derivatives (Heussner et al., 2015

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This hydrogen bonded network is stabilized by the sum of all the hydrogen bond energies, and if nonpolar molecules such as hexane were inserted into the network they would destroy local structure without contributing any hydrogen bonds of their own