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Among antioxidant enzymes, our recent studies have shown evidence of impaired functioning of the enzyme paraoxonase 1 (PON1) associated to high-density lipoprotein (HDL) in individuals with AD, with reduced protein levels and enzyme activity (60, 61)

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Unlike stimulants, it is non-addictive and non-sedating, though long-term human data are still limited

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Material obtained outside controlled research supply chains is not characterized to the same standard, and identity, purity, and endotoxin status can vary substantially between sources