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Off-Label Demand, On-Label Costs GLP-1s are clinically appropriate for some members, particularly those with type 2 diabetes or obesity-related health risks

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Both sEVsemaglutide and sEVtirzepatide significantly reduced blood glucose levels compared to the control group (Figure 5), suggesting that sEVs may play a similar role as SNAC in enhancing the oral availability of semaglutide, thereby reducing blood glucose levels

Oxidation was stopped by the addition of 1 mM EDTA (Fluka) and cooling in ice