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HMIT differently controls inositol transport and signaling in the neurons and astrocytes along with SMIT1 and SMIT2, which may stand for a specific role of inositols in osmoregulation, insulin signaling, Ca 2+ mobilization, and membrane composition in the brain [52,53,54,55]

When this symbiotic relationship is destroyed (such as gastrointestinal surgery, application of antibiotics, application of immunosuppressive drugs, etc.), it will cause dramatic changes in gut microbiota, leading to gastrointestinal dysfunction, and may be infected with other diseases (42, 47) (Figure 1)

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Anti-inflammatory constituents of Robinia pseudoacacia Root Bark