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Discussion To our knowledge, this is the first study to demonstrate an increase in CNS GSH levels with a noninvasive GSH augmentation strategy

Regulation of other signalling pathways LA can inhibit the production of proinflammatory nuclear factor-kappa B (NF-B) [39] and stimulate the translocation of glucose transporter 4 (GLUT4), thereby improving insulin sensitivity [40, 41]

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GEF means go: turning on Rho GTPases with guanine nucleotide-exchange factors

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