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Notably, the results demonstrated that UA exerts its effects by downregulating microtubule-associated proteins 1A/1B light chain 3B and Lysosomal-associated membrane protein 1 expression, without significantly altering PINK1 and Parkin protein levels (36)

Favero G, et al

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Chronic exposure to topical steroids can suppress the hypothalamic-pituitary-adrenal (HPA) axis, leading to decreased production of endogenous corticosteroids by the adrenal glands

doi: 10.1038/nmeth.1212 17 HalseyT