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L.et al (2022)
Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth
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Thus, any impairment to either of the system Xc -glutathione-GPX4 axis compromises the conversion of lipid peroxides to the corresponding alcohols, ultimately hampering the GPX4 antioxidant effect and giving rise to ferroptosis ( Nuclear factor erythroid 2-related factor 2 (Nrf2) has been found to be a key regulator in inhibiting ferroptosis
Ammonium hexafluorophosphate (83 mg, 0.5 mmol) was added to the solution, which was then stirred for 1 h
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