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On my packets of Hydroxocobalamin which i get from Germany , it is printed

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Because the intranasal forms have lower absorption than the IM dosage form, intranasal B12 forms are administered once weekly

This combination is not suitable if you have hyperthyroidism, because both Phentermine and hyperthyroidism increase catecholamine (adrenaline) levels in your body, which can worsen symptoms like rapid heart rate, hypertension, anxiety, and weight loss