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It ensures that thymic epithelial cells express proteins from tissues throughout the body, allowing the thymus to test developing T cells against a comprehensive library of self-antigens

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In the NSC model, vimentin is implicated in spatial organization of proteasomes and autophagosomes to the aggresome domain, possibly anchoring machinery that promotes degradation of aggresome contents 59

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[DOI] [PubMed] [Google Scholar] 86.Yubisui T, Takeshita M, Yoneyama Y