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Arrows indicate stimulation (green), inhibition (blue), and the resulting cardiovascular effects (red)

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Inhibition of beta-TrcP-dependent ubiquitination of p53 by HIV-1 Vpu promotes p53-mediated apoptosis in human T cells

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When Yuyang Liu, a graduate student in his lab and first author of the study, compared SLC25A39s structure against others in the SLC family of transporters in the AlphaFold protein structure database, Liu spotted a unique extra loop in the protein