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This dynamic, tumor-favorable redox balance established by high concentrations of GSH and H 2 O 2 in the TME not only inhibits ROS-based therapies but also indirectly causes immune suppression

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The evolutionary conservation and functional specialization of GPx isoforms underscore their critical role in cellular defense, ensuring protection across cellular compartments and enabling tailored antioxidant defense in specific tissues [8, 9]

Multi-omics reveals mechanisms of total resistance to extreme illumination of a desert alga