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The results showed that compared with insulin glargine, Tirzepatide showed better HbA1c and weight reduction in the population of type 2 diabetes patients in the Asia-Pacific region (mainly China): HbA1c reduction of up to 2.49% and weight reduction of up to 7.2 kg (9.4%) at 40 weeks of treatment, significant improvement in blood lipids and blood pressure, and overall safety and tolerability were good

Yabut JM, Drucker DJ

Serum amyloid a induces interleukin-1beta secretion from keratinocytes via the NACHT, LRR and PYD domains-containing protein 3 inflammasome

Further Hormone Combinatorial Approaches with Promising Data Other combination pharmacotherapies based on gut hormones have shown positive effects in preclinical models