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Magnetic Resonance Spectroscopy MRS is a relatively new tool that is used in conjunction with MRI to non-invasively measure the concentration of metabolites within living tissue ( 3 ( 3 voxel makes it incredibly difficult to get a pure white matter location and virtually impossible to obtain a pure grey matter placement ( In light of the evidence for extensive structural and functional brain abnormality in schizophrenia ( Interaction of Oxidative Stress and Current Schizophrenia Hypotheses The Dopamine Hypothesis The dopamine hypothesis is the most well-known in schizophrenia and has dominated the literature for many years

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