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In a large clinical trial in about 230 patients with OHE, preliminary data shows that the administration of OCR-002 results in a dose-dependent significant reduction in ammonia and an improvement in the severity of HE (unpublished data

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Preclinical studies, primarily conducted in rodent models, provide essential proof-of-concept data regarding mechanism of action, biodistribution, and preliminary efficacy

15 Potential Additional Benefits Several studies have investigated potential additional benefits of DPP-4 inhibitors, including microvascular and macrovascular effects, effects on blood pressure (BP) and weight, and risk of hypoglycemia

Even though this condition keeps most peptides stable for several years, peptides long-term stability is at risk when peptides expose to moisture, therefore, the vial should be tightly capped at all times