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Let's have a closer look at how vitamin B12 can be used as a hangover cure

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Additionally, oxidative stress significantly impairs RFC function: Low glutathione: Reduces RFC function ~20-40% High nitric oxide: Reduces RFC function ~35% Hyperglycemia: Reduces RFC function ~20-35% Even if you're taking Leucovorin, oxidative stress can prevent it from reaching your brain

This isnt necessarily a bad thing but you need to be aware of it

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