TMRCP may be another metric to define the clinical meaningfulness of C-peptide, meaning it could be an alternative endpoint to consider for future DMT trials
(6) Why
The presentation of the spinal cord was recorded in deeply anesthetized rats, with a camera attached to a VMS-004 Discovery Deluxe USB microscope (Veho, Denver, CO, USA), before the procedure in normal, healthy rats (before injury induction) and then, in spinal cord-injured rats, before therapy application at 10 min or at day 4 after injury, and then at 1 min, 5 min, 15 min, and 20 min intervals after therapy application, before the animals were sacrificed
The label expansion was supported by two Phase III trialsa 12-week induction study and a 52-week maintenance studyboth of which met the primary endpoint of clinical remission
It is also frequently referenced within longevity peptides protocols and advanced peptide stacks for sale involving anti-aging and cellular-signalling research