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This three-phase randomized controlled clinical trial involves 1961 overweight or obese adults (none of them suffering from diabetes, average weight 105 kg, average body mass index 38 kg/m2), the clinical trial was conducted at 129 sites in 16 countries in Asia, Europe, and North and South America

(Bethesda, MD: ClinicalTrials.gov) (2024)

In practice, it often leads to: Loss of strength Reduced muscle mass Poor workout recovery Fat loss plateaus Carbs help preserve muscle

Types of Weight Loss Medication Available in the UK MHRA-regulated options include orlistat, GLP-1 receptor agonists (semaglutide, liraglutide), and naltrexone/bupropion (Mysimba)

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