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In the case of water-soluble vitamins like B12, vitamin C, folic acid, and other B vitamins, some medically reviewed literature points to early morning as the optimal time to take them as they can be taken on an empty stomach, but more peer-reviewed research is needed to confirm this claim

We use the model to study the extent of liver damage caused by overdoses or by chronic use of therapeutic doses, and the effects of polymorphisms in glucoronidation enzymes

Sofic, E., Lange, K

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