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Allow absorption: After administering the nasal spray, allow the subject some time to naturally absorb the TB-500 formulation

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Gastrointestinal symptoms Tongue soreness, appetite loss, and constipation have also been associated with vitamin B 12 deficiency

The American Society of Interventional Pain Physicians (ASIPP) grading of evidence has been utilised in order to appraise the level of evidence provided by studies with a similar outcome addressed in this review [18]