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Out of 41 RCTs, 39 studies have shown a significant lowering effect of L-carnitine supplementation on FBG (mg/dl) (16, 17, 23, 43, 4569, 7180), 19 studies on serum insulin (pmol/l) (16, 43, 44, 51, 5355, 57, 59, 61, 63, 68, 7176, 80), 20 studies on serum HbA1c (%) (16, 17, 23, 45, 48, 49, 5355, 57, 58, 61, 63, 66, 67, 71, 74, 77, 79, 80), and 17 studies on HOMA-IR (43, 44, 49, 50, 5457, 59, 61, 63, 68, 7073, 75)