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Biochimica et Biophysica Acta (BBA) - Enzymology

People with late complications of type 1 diabetes As there is no evidence that intensive glycaemic management slows the progression of late microvascular complications of diabetes, glycaemic targets in individuals with advanced complications should be individualised and based on the balance of risks and benefits [39, 275]

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All formulas used for imputing the missing values were provided in the Cochrane Handbook for Systematic Reviews of Intervention (Version 6.5, Section 6.5.2.8)