Unlike the mice, the human participants were allowed to eat as much as they wanted (albeit with what appears to be the usual guidance to restrict calories and at least try to lose weight that way3)
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Pyke C, et al
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[35] T2D is a progressive metabolic disorder characterized by insulin resistance, impaired insulin secretion, obesity, diminished incretin response, dyslipidemia, [3, 69] and ultimately in -cell dysfunction