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Force and membrane potential in acetylcholine and potassium contractures of denervated mouse muscles
A treatment-related increase in malignant thyroid C-cell carcinomas was observed in all male liraglutide-treated groups with incidences of 2%, 8%, 6%, and 14% and in females at 0.25 and 0.75 mg/kg/day with incidences of 0%, 0%, 4%, and 6% in 0 (control), 0.075, 0.25, and 0.75 mg/kg/day groups, respectively
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This indicates that patients may still experience the appetite regulation benefits of GLP-1s, even at lower doses, and the effects may be more gradual and gentler, which could be beneficial for long-term adherence